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KMID : 1234520080030010095
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Korean Journal of Urogenital Tract Infection Inflammation
2008 Volume.3 No. 1 p.95 ~ p.98
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Preliminary Study on Protective Effect of Urovaxomⓡ in the Longterm Urinary Catheterized Patients
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Yoo Jae-Yeong
Shim Bong-Suk
Yoon Ha-Na
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Abstract
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Purpose: Catheter associated urinary tract infections are a major health concern in chronic catheterizing patients due to the complications and frequent recurrence. In this study, we aimed to investigate the effect of conventional Urovaxomⓡ administration in chronic urinary cathterizing patients in respect of prevention of recurrent symptomatic urinary tract infections (UTIs).
Materials and Methods: Subjects were adult male and female patients who have been catheterized for urinary drainage with any pathologic reason more than 1 month. Among 15 eligible patients 13 patients (2 males, 11 females) were enrolled to this study. Urovaxomⓡ was parenterally administered at least for more than 3 months. Before and after three months of drug administration urinalysis and urine culture tests were followed.
Results: There were no significant adverse effects with Urovaxomⓡ administration during the study period. All of the 13 patients showed clearance of bacterial growth after taking Urovaxomⓡ eventhough some of them showed persistent microscopic hematuria or pyuria.
Conclusions: UTIs and their associated complications are one of the bothering problems in chronic catheterizing patients. Urovaxomⓡ showed positive effect in preventing UTIs recurrence in our small group study, eventhough further research will be required. Urovaxomⓡ administration will give beneficial effect in some selective patients with chronic catheterization.
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KEYWORD
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Urinary cathter, Urinary tract infection, Uro vaxom
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